This is an observational study of adults who are opioid naive and are receiving new prescription of opioids for acute pain. One enrolled, participants wear a sensor (smartwatch) for up to 30 days while receiving opioids, give blood samples at 0, 30, 60 and 90 days, and take surveys at various time points throughout the year. The physiologic data from the wearable sensor will be used to develop digital biomarkers of opioid dependance, and the blood sample will be tested for levels of various serum growth factors. Both digital biomarkers and serum growth factors will be analyzed with respect to long term outcomes (development of OUD, long term opioid use, and development chronic pain). The overall goal is to develop strategies for early identification of those at risk for opioid related adverse outcomes.
Residents can help screen and enroll ED and pre-op patients who are newly prescribed opioids for acute pain, consent them, draw blood and administer surveys. Most activities on this project are in person.